MOD Awardees Profile プロフィール
氏名：原野 謙一
Name：Kenichi Harano
現所属：国立がん研究センター東病院先端医療科/乳腺腫瘍内科
Current working institution (Department / Section)：Department of Developmental Therapeutics/ Breast Medical Oncology, National Cancer Center Hospital East
留学時所属：日本医科大学武蔵小杉病院
Institution where employed when he/she went abroad for MOD：Nippon Medical School Musashikosugi Hospital
Professor Naoto T Ueno出身大学：京都府立医科大学
Graduate school：Kyoto Prefectural University of Medicine
研修先(MOD institution)：The University of Texas MD Anderson Cancer Center
研究室(Laboratory at MOD institution)：Department of Breast Medical Oncology
メンター(Mentor)：Professor Naoto T Ueno
研修期間(Dates)：7/29/2014-3/14/2016
研究テーマ(Research theme)：
Identification of prognostic factor and potential treatment strategy in inflammatory, HER2 positive, and triple-negative breast cancer. 炎症性乳がん、HER2陽性乳がん、トリプルネガティブ乳癌における予後因子同定、新規治療開発
研究成果(Research result) -Article/Presentation at the congress論文・学会発表-：as of August, 2018
Clinicopathological and surgical factors associated with long-term survival in patients with HER2-positive metastatic breast cancer.
Breast Cancer Res Treat. 2016 Sep;159(2):367-74.
2) Huo L, Wang Y, Gong Y, Krishnamurthy S, Wang J, Diao L, Liu CG, Liu X, Lin F, Symmans WF, Wei W, Zhang X, Sun L, Alvarez RH, Ueno NT, Fouad TM, Harano K, Debeb BG, Wu Y, Reuben J, Cristofanilli M, Zuo Z.
MicroRNA expression profiling identifies decreased expression of miR-205 in inflammatory breast cancer.
Mod Pathol. 2016 Apr;29(4):330-46.
3) Harano K, Kogawa T, Wu J, Yuan Y, Cohen EN, Lim B, Reuben JM, Ueno NT.
Thrombocytosis as a prognostic factor in inflammatory breast cancer.
Breast Cancer Res Treat 2017; 166: 819-32
4) Fujii T, Matsuda N, Kono M, Harano K, Chen H, Luthra R, Rou-Chowdhuri S, Sahin AA, Wathoo C, Joon AY, Tripathy D, Meric-Bernstam F, Ueno NT.
Prior suystemic treatment increased the incidence of somatic mutations in metastatic breast cancer.
Eur J Cancer 2018; 89: 64-71
5) Ding Q, Wang Y, Zuo Z, Gong Y, Krishnamurthy S, Li CW, Lai YJ, Wei W, Wang J, Manyam GC, Diao L, Zhang X, Lin F, Symmans WF, Sun L, Liu CG, Liu X, Debeb BG, Ueno NT, Harano K, Alvarez RH, Wu Y, Cristofanilli M, Huo L.
Decreased expression of micro RNA-26b in locally advanced and inflammatory breast cancer.
Hum Pathol 2018; 77: 121-129
6) Kogawa T, Fujii T, Fouad TM, Liu DD, Harano K, Masuda H, Iwase T, Barnett C, Park YS, Lim B, Tripathy D, Litton JK, Ueno NT.
Impact of change in body mass index during neoadjuvant chemotherapy and survival among breast cancer subtypes.
Breast Cancer Res Treat 2018; Jun 18 Epub ahead of print.
